Bigfoot DNA Study Reveals Unknown Paternal Lineage and Ancient Origins

Posted Saturday, June 27, 2026

By Squatchable.com staff

So, I just stumbled across this wild conversation between Joe Rogan and David Paulides, and honestly, if you've been following the Bigfoot DNA debate at all, this is one you absolutely need to check out. Paulides, who's known for his Missing 411 work, drops some seriously fascinating details about a $400,000 DNA study that most people have probably never heard about. Here's the backstory that makes this whole thing so intriguing. Paulides was approached by two guys who had completely separate childhood encounters with Bigfoot. They didn't know each other back then, but they both had these experiences while camping with their families in different parts of the country. Years later, they ended up working together, made millions, and discovered they shared this same wild story. That's when they decided to hire Paulides, who has an investigative background, to look into whether Bigfoot was real, false, or a hoax. They told him to take his time and they'd foot the bill. He turned them down multiple times before finally agreeing when his personal life opened up some space. The investigation kicked off in the Great Smoky Mountain National Park in Tennessee, where Paulides met a man named Scott Carpenter who showed him areas packed with footprints and hair samples. This is where things get clever. Paulides and his team came up with a method to collect better hair samples, specifically ones with follicles attached, because you need that for proper DNA analysis. They wrapped packaging tape inside out around trees, placed food like honey at the forks, and when Bigfoot leaned against the tree to grab the food, the tape would pull hair out with the follicle intact. Brilliant, right? When they sent those samples to hair and fiber experts, the experts were baffled. They'd never seen anything like it. The hair didn't match any known animal classification. Paulides then tried to get major universities involved, UC Davis, University of Texas, and several others, but none of them would touch the samples. Eventually, he found Dr. Melba Ketchum, a DNA expert who testified in Texas courts. She agreed to analyze the samples, and after getting her hair and fiber experts to confirm the samples were unknown, she asked for more. Paulides went coast to coast collecting samples, and they ended up with 125 valid samples that weren't deer, elk, bear, or any other known animal. The DNA analysis cost around $400,000, which was a hefty price tag back then. And here's where the results get really interesting, and honestly, kind of mind-blowing. The maternal DNA traced back 12,000 to 15,000 years to the Middle East. The paternal DNA, though, doesn't exist in Genbank. We're talking 352 billion base pairs that match nothing known to science. Ketchum's interpretation was that around 15,000 years ago, an unknown hominin male population interbred with modern human females, creating a hybrid lineage that continues today as Sasquatch. Now, I know what you're thinking, because the skeptics in the comments sections everywhere brought this up too. Ketchum's study was published in a journal called Denovo Scientific Journal, which she essentially controlled herself. It wasn't a traditional peer-reviewed publication. Critics pointed to potential contamination and poor lab practices as explanations for the unusual results. The mitochondrial DNA being 100% modern human is exactly what you'd expect from contaminated samples, they argued. But Paulides pushes back on this in the conversation, and honestly, his argument makes a lot of sense. If the samples were contaminated by humans, the paternal DNA would show human markers. It wouldn't show nothing. The fact that it shows nothing is actually the most compelling part. Plus, no other lab has tried to replicate the study, which Paulides points out is unusual. If the results were so obviously flawed, you'd think someone would want to prove it definitively. The conversation also touches on the idea of human interbreeding with other hominins, which isn't as far-fetched as it sounds. There's actually legitimate scientific discussion about Neanderthals potentially being the result of humans breeding with another ancient hominin, rather than humans breeding with Neanderthals. The genetic research into ancient human relatives is constantly evolving, and the idea that unknown hominin species could have contributed to modern human DNA isn't outside the realm of possibility. This is definitely worth watching if you haven't seen it. The discussion goes deep into the methodology, the results, and the implications. Whether you believe the DNA study or think it's flawed, the conversation raises questions that deserve more investigation. And the fact that nobody has tried to replicate the study, either to confirm or debunk it, is something that should probably bother everyone in the scientific community. Check out the full conversation when you get a chance. It's one of those interviews that stays with you and makes you think.